Captique™ Injectable is the newest FDA-approved non-animal stabilized hyaluronic acid dermal filler. The way your skin looks is directly related to the way your skin is supported. As we age, the natural support layers in the skin break down resulting in the formation of wrinkles. Captique™ gel, a clear gel containing a purified form of hyaluronic acid, adds volume lost during the aging process by temporarily smoothing out facial lines and wrinkles.

Captique™ gel is injected just under the skin's surface in order to temporarily correct wrinkles. Treatment results are immediate. Over time, the gel will gradually break down and be naturally absorbed by your body. After the initial treatment, an additional treatment of Captique™ gel may be necessary to achieve the desired level of correction. The need for an additional treatment may vary from patient to patient. Your physician will work with you to develop a treatment program to meet your individual needs.

What is Captique™ gel used for?

The gel is injected into the skin tissue for correction of moderate to severe facial wrinkles and folds such as nasolabial folds and marionette lines (also known as smile lines).

Where does Captique™ gel come from?

The gel is produced from materials of bacterial origin and contains extremely small amount of bacterial protein. Because of this, you should speak to your physician and you should not use Captique™ gel if you have any known allergies to bacterial protein.

How does Captique™ gel work?

Captique™ gel is injected just beneath the skin surface temporarily adding volume to the layers of the skin that have deteriorated due to age and other factors. The gel, when injected, is used to raise depressions in the skin, providing temporary correction of wrinkles and folds.

What is involved in Captique™ gel treatment?

In general there are three steps: a consultation with your physician, a series of treatments (injections), and periodic touch-up treatments.

Do the injections hurt?

In general, injections may cause some discomfort. Captique™ gel is injected directly into the skin using a fine needle to reduce injection discomfort. Physicians may choose to anesthetize the treatment area to further minimize discomfort. Please consult your physician.

Is the product safe?

Yes for most people. The primary ingredient in Captique™ gel is hyaluronic acid (a component of skin) produced from materials of bacterial origin. Captique™ and its counterpart Hylaform® have undergone extensive testing including scientific studies to establish safety and effectiveness. The gel has been approved for injection into the skin for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds) by the U.S. Food and Drug Administration (FDA).

Can anyone be treated with Captique™ gel?

Your physician will ask about your medical history to determine if you are an appropriate candidate for treatment.

How will my skin look and feel immediately after treatment?

Most people feel comfortable in resuming their normal activities following treatment. Temporary puffiness of the treated areas, however, should be expected.

As with any injection, you may also notice temporary redness, slight bruising, and tenderness around the treatment sites. Like the puffiness, these are normal occurrences and all should clear up within a few days. Although the injected material is generally not visible through the skin, some people have reported that they were initially able to feel the outline of the injected material.

When should I notify my physician?

Be sure to report any redness and/or visible swelling that lasts for more than a few days or any other symptoms that cause you concern to your physician.

What concerns should I have after treatment?

Your physician will review with you what to expect following treatment with Captique™ gel. If there is swelling or redness after the injection you should minimize your exposure to sun and UV lamps. Within the first 24 hours, patients should avoid strenuous exercise, extensive sun or heat exposure and alcoholic beverages as exposure to these may cause temporary redness and swelling at injection sites. Make-up may be applied a few hours after treatment if no complications are present such as open wounds, bleeding and infection.

When may I apply make-up?

Make-up may be applied a few hours after treatment if no complications are present such as open wounds, bleeding and infection.

Does the correction last forever?

No. Correction is temporary, therefore, touch-up injections as well as repeat injections are usually needed to maintain optimal correction. The need for touch ups will be influenced by ongoing mechanical forces (such as smiling or other muscle activity) and biological changes (such as aging) that caused the original skin depressions.

How often will I require treatment?

Everyone's skin is different. That is why the timing of any additional treatment varies from person to person. Over time Captique™ gel will be absorbed by your body; this is why you may want ongoing treatments. If you choose not to continue with your treatment, any remaining gel is simply absorbed by your body over time and your skin gradually returns to its natural shape.

Without touch-up injections, how will my skin look?

Correction will reduce gradually until your skin looks like it did before treatment with Captique™ gel. Touch-up injections will help you maintain correction of the skin surface.

What else should I know about Captique™?

• Captique™ gel is indicated for injection into the skin for correction of moderate to severe facial wrinkles and folds (such as the nasolabial folds, the lines that run from the nose to the corner of the mouth).
• The safety and effectiveness of Captique™ gel use longer than one year has not been evaluated in clinical trials.
• As with all injections into the skin, the injection of Captique™ gel has a risk of infection.
• The safety of Captique™ gel for use during pregnancy, in breastfeeding females or on patients under 18 years has not been studied.
• Captique™ gel should not be used in patients with a known potential for keloid formation or hypertrophic scarring (heavy scarring) or pigmentation disorders.
• Captique™ gel should be used with caution in patients on immunosuppressive therapy.
• Patients who are using substances that can prolong bleeding, such as aspirin, non-steroidal anti-inflammatory drugs and warfarin may, as with any injection, have increased bruising or bleeding at injection sites.
• After receiving injections of Captique™ minimize exposure of the treated areas to excessive sun, UV lamp exposure, and extreme cold weather, until any swelling and redness have disappeared.
• If laser treatment, chemical peeling or similar procedure is considered before or after treatment with Captique™ gel, there is a possible risk of an inflammatory reaction (such as redness, swelling) at the Captique™ injection site.

For more information on this product please visit www.inamed.com

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